Pet Wellbeing Milk Thistle for Cats - Supports Liver Health, Protects Liver - Glycerin-Based Natural Herbal Supplement - 2 oz (59 ml)

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Good Manufacturing Practices: All of our formulas are manufactured in a facility that adheres to Good Manufacturing Practices.

Milk Thistle is a natural, herbal supplement that is gentle enough for long-term use. Why choose Pet Wellbeing Milk Thistle for your feline friend? Diabetes: The silymarin in milk thistle has been shown to decrease blood sugar and hemoglobin A1C ( 1, 2). Pets suffering from diabetes are often given milk thistle at least once per week. This decreases the amount of insulin they need daily ( 1). The insulin sensitizers come from a family of compounds called flavonolignans ( 2). Silymarin acts as an inhibitor of aldose reductase enzyme, thus interfering with accumulation of sorbitol which accumulates in the presence of high blood sugar and promotes diabetic complications. Silymarin is potent agent against insulin resistance and diabetes-induced high blood sugar. Varzi, H.N., Esmailzadeh S., Morovvati, H., Avizeh, R., Shahriari, A., and Givi, M.E., (2007). Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs. J Vet Pharmacol Ther, 30(5):477. Abstract retrieved from https://www.ncbi.nlm.nih.gov/pubmed/17803742Silybin is the major active component of silymarin, which is found naturally in the milk thistle plant. Silybin acts as a liver protectant chiefly through preventing toxin penetration into liver cells. It also inhibits toxic and inflammatory effects on cells, and acts as an antioxidant and free radical scavenger. Despite that, well-designed clinical studies, such as randomized, double-blind, controlled trial, with an appropriate cohort of patients or adequate dosages of aforementioned compounds, tested as single agents or in combination, are scarce in veterinary medicine. Moreover, the vast majority of molecules to which “hepatoprotective” properties are attributed are mainly included and marketed as complementary feed. These are also intended as nutraceuticals, where a nutraceutical has been defined as “a food or part of a food, such as a dietary supplement, that has a medical or health benefit, including the prevention and treatment of disease” (Interview De Felice, 2011) [ 5] or as functional foods [ 6]. Interestingly, an international agreement on their definition has not yet been reached [ 6]. Mellit – has herbs that may help to reduce the blood sugar levels, regulate metabolism, and balance the organs against the pancreatitis symptoms.

Turmeric – rich in curcumin property to help support the body against inflammation and pain throughout the body Milk thistle is an herbal remedy derived from the flowering daisy and has a regenerating effect on the liver. It helps cure liver diseases and fight the toxic effects of different drugs. Milk thistle stimulates the regenerative properties of the liver. Its main active ingredient is an anti-oxidant. Milk thistle comes both in the form of pills and in a liquid form, so it can be easily administered. Milk Thistle for Cats Herbal dietary supplements are beneficial to the health and wellbeing of your pet and are safe for long-term use. Every pet responds to natural herbal supplements differently, therefore it is important to be consistent and administer the product daily. Supplements generally take two to four weeks to take effect, however this will vary from one animal to the next. Shake well before use. The easiest method is to use the dropper provide and places the drops into your pet’s food or favorite treat. You can also use the dropper and squirt directly into the pet’s mouth.

Denamarin may also be used when treating toxicities that affect the liver, including acetaminophen toxicity. There are also some medications necessary to use to treat some types of diseases, and these medications may put additional stress or strain on the liver. Denamarin can be helpful in protecting the liver from some of these effects while the medication is being used. Side Effects of Denamarin for Cats While SAMe and silybin/silymarin (or milk thistle) can be found in supplement form for humans as well, these products can have a great degree of variability in active ingredients and are not designed for pets. Raloxifene (Evista). Milk thistle may affect how your liver processes this osteoporosis medication, causing higher levels of the drug in your bloodstream. Talk to your doctor before taking milk thistle if you're taking raloxifene. Milk thistle has proven to be useful in acetaminophen toxicity in cats whose well-meaning owners have dosed them with the drug for their aches and pains ( 8).

Denamarin is a liver health supplement that contains the two main ingredients s-adenosylmethionine (SAMe, pronounced “sam-ee”) and silybin. In the past, we’ve had furparents reach out to us to let us know they were able to reduce the dosage of their pet’s medication while using our Mellit formulation, however, we only suggest doing this under the supervision of your trusted veterinarian. Silymarin reaches high levels in the bile and liver (it also reaches significant levels in the lungs, pancreas, prostate, and skin). It can be used in the treatment of feline hepatic lipidosis, chronic hepatitis, cholangitis (inflammation of the bile ducts), and pericholangitis (inflammation of the tissue around the bile ducts). It may be useful in preventing or treating gallstones by thinning the bile.Denamarin helps to protect liver cells from toxins and inflammatory damage, and improves liver function. Milk Thistle also helps to maintain the stability of cell membranes of liver cells. This structure of the cell is essential to protect it against damage and prevent the infiltration of toxins and infectious agents. Fortunately, side effects to Denamarin appear to be minimal. Toxicity studies have shown no adverse effects in pets at typical doses that are prescribed, and overdoses are unlikely to cause serious illness. In people, side effects of SAMe are also, rare but vomiting and decreased appetite have been reported. NHV’s certified organic Milk Thistle is a safe herb that is recommended and used by holistic practitioners. All of our products are all-natural and formulated by veterinarians with a focus on comprehensively supporting the health and well-being of your feline family member. Habib, R. (n.d.) Milk thistle for your dog. Dogs Naturally Magazine. Retrieved 2/7/2020 from https://www.dogsnaturallymagazine.com/milk-thistle-for-your-dog/